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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd1c3bab52c0501f10d043e53a173f57ef5f2f8133775795d497e011eeff1499' 
  AND token = 'kh//skxt7ZCI2FnieeFOVzApVOwlHtbrfRiojn/UnC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}