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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801f1010b596547f4c4f57b228dfb4f41ff113ac7fb10594c79194cb45d5241c' 
  AND token = '9ggHoVqFHz1oyJka/46qI4zLD4K73SmaFbpA+NRYxXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}