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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d47e7f8258e583c05a72537e2ba665cc73ab69093644346a5f78b8b73e03af7' 
  AND token = 'asTMMmEfPjK1q/A5+TjLWFiBBIgXAGGLgcx2Ttq6Eg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}