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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881d4228d435e761fd4773e6fcca5b87e39972bfe361fa1fd1210a2f7b8baf16' 
  AND token = 'u0sHHOYFtpK7D4OPb17Mm5prgcKn2bc69sZhqrUMv9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}