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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1f4e6ce6c4c59e573e78959cd3d266896d1477e5426473a9e0244ad8665940' 
  AND token = '+JqeMOeRizY/nftiaBO1bI1irF1TDuouldmhD73E/eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}