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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0c25da96fe6230d705f009e25b284017b511c8c3505c5d66dfe316b60d02aff' 
  AND token = '6x1LJg2K1XtHL1FAJUTxIfec1U8XFAND8CZgAo0/MzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}