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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc2199418c28065da08e5399b5f2a63b821bef593de5af807b39a50da3e836de' 
  AND token = 'PCM85snKHKGjr6PPkLnZ+UFJF4r2RI0iv10Yo0HPlm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00111

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}