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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4405510175707457371dd22b868e78c340049f7b4ee10da3a5ff1096ba3e879a' 
  AND token = 'TfmGYy/HeeZUp8b5be7hZ//EfPs5fXmmOdcZZHAqqPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}