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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba78706e3a89be3bb30cd836d9d7328be46903d13ab39b15d779b2eea17be69f' 
  AND token = 'V5gPVy5hpVrVbKB+4CgXkHRp6ofBRFwCRzQKenuHvlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}