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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cfb2b042ecc8654728c490a656594c84b3132d5625c4ff6868fc92a28bd75d4' 
  AND token = 'Ag/UdALgTJVth4Ib+l6kN/B2O3g6vUMXJDzKx510xgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}