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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c21d4a168931a32f6dd5e3693ec62d65c7fc189331ab69c203bc8f7d33c9cab' 
  AND token = 'w3oL/Kq1fIjC40avAcWzUc3XweGzxFAh1SsgJbjVyqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}