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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4811612af76dab28433cbb427c9fac48cadf84b608028441deeae14d234e181' 
  AND token = 'PUJ7/F/KHHuA6L6JDbn4VI61iSzLWcfvTyMdtgFazLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}