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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea5d5fa4ded144c168dbab88f7e6afea3ce20fa4aec1a3d771856d54289afb7' 
  AND token = 'pWE6oe1mgtGSV24gRbr5r5yrFwbkoT88+DQeVw7wgQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}