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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a54d7a414119e5d4b8494b73a9eff8a9328beef3a2f40c4b3d830810a13e5a3' 
  AND token = 'QrSv+wGmRAqRmjwUqPy7DJOdzMWVq4wwyf1mE1D4DLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}