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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1450fe4d8006f4dffbd6ef8c6b71652b851c4230a11809eed65f77d236037556' 
  AND token = 'AC5fxMumzRvmMd2yxYXdy1S1hyvPNQBBNp8dtiOAMvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}