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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d4dfc6a3ac38eff9d165eb768c32204f89d100c7f99125a42c76cb007596496' 
  AND token = '3mlPsClkomjTr8+9teFWjDjsoyS5e4GbOa1j7BY86oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}