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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd57ad9cc3efa5b5c42afad2701162f4cb3051caff2c167b9d9130865ee288637' 
  AND token = 'U7DCGpEVZtV9Fb2Sf3+egYjc6BipsWq3dgiuSE1DCh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}