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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d8e5684d403cc34abbebd6ce4c5e41d452f5f0362d7987c4d6d53ef1b304894' 
  AND token = 'H2ahH9nHl4higREigl761BqnOLzs76Wvi93XAG01YHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}