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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e32ec3ba787253f0666dd5a0cdd6b446c1f8dfb128e55175a27ec50ab75935d0' 
  AND token = 'kySqyGAvoU8js+YGOEnfxw3Fj0WLpjSkBnUkIjz25wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}