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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37cc5d2acdc67c719474a573955c95d7c81c4d506368de7e0c3c337f6b5da638' 
  AND token = 'p+JFRI5+qoiW6zOu+Rt56Yq4vQFPgzPKfU+xUdVRXJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}