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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e972a93980ff4ae2d742aaf8e9085a93825d21b1ad1b6bbf5573ada0aab5b910' 
  AND token = 'vmetoOGbdDP+B3Ge7jYbP6XwDeM/wBx4ES7Yv1L35ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}