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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd52a4a1549dbd4bab3c1fac8c9c1944597e49fac0417bee01c2590f20019a04' 
  AND token = 'vxztj7All9YK1TJAg793Hz0H1HZ7CfSNnEtscc5x7vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}