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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80d3c49fe209529f4f823155ff6a459bb90c7eda720a205786fd924554d6dac' 
  AND token = 'zXSj4Haem6611/9Cx87r0xtotEXcXDW79Ck2ciALLII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}