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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24f0ab1b24f771b1bd4013121fcd1b7d89b4748d30c9bb672955350b797c1650' 
  AND token = '03MjwHJChC5PkEepqxuqSLj6LRriofPsdd4LsThEUUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}