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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25387d75b13c53c7db0780b55fd1ebb5f34627b1d6e4e88b48ae1e2a51f5fd4' 
  AND token = 'o0wptrL0X0KY0oorZpD/wOaeU7oABhr8Y9Zd1xxlIww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}