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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a35c80c812a144bcc0e0be0fe8ae895e4a3caaa3e2b63c13306534b154f999' 
  AND token = 'Ta2p838AMx64l6bYUcR9VhTw78ikuMP4qhVwFHPVXxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}