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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ebbd0341f0c2d8d1c3b931eaafeeb9df1720132e65ceb47d91a70af375d9e41' 
  AND token = 'N8tta1y9MzOLOGGwsLT71GRq9AgHV3MA6YwQHRs4ZH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}