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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d6a249d6fa503cdf19f9400d5b9679ac2370fb5c5f04fc372ce2650c2712fc' 
  AND token = 'i7Wv0RCvpsNwDKHlqxl/nDHo8Vfnl8v/2egynhXVmmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}