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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a177fa7274d306de6d941aa77f9b41c5f554e80cb1d0306b6d2c72e57ecfefb8' 
  AND token = 'zT1k7+l7cM1s5W2vnFiYS+2ZUbvzEHyPrZm72zMMoc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}