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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b53713c293a1f1d181a085c1da8c74501dfcc1e7847984b47642515b1f8d60e' 
  AND token = 'oHUmAOj/iMCII6hmb8BKgejTDFWG1eih5Zs6brXpJGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}