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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ad2015ce86471ec4d372ef734db9fbe3586c701a58159b1de75aa23d8449a3' 
  AND token = '4QLeumtmZUVOnRSATZn9KHn5c52m3EYeJNLPUw3xFJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}