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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789a002cdac460400e69f9d00e11feea47d0c0dbc48dd394b415db13da1b570a' 
  AND token = 'kTUu5YxwGFRmLgiaj7vv/63eMdROovMJGphMDg5BwB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}