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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d6ea5f614873762eb4132187337081dc01b2a4a763074ffdb927b131cf1da7' 
  AND token = 'cSOGgX9G3TbB4DEGxCT5JQxMq9SSK2oJBGTmfO3HiJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}