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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621eb725e22c8eaba393a0a3c47e30c066983885b44e8b225e713fbb4816b98a' 
  AND token = 'CeZqS5c2WwXeNN/JQuJrJeUY2bBkUVKDK7td+jDSm3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}