SELECT 
  product_id, 
  group_id 
FROM 
  cscart_product_variation_group_products 
WHERE 
  group_id IN (
    45, 340, 273, 66, 219, 284, 161, 272, 158, 
    307, 268, 350, 115, 320, 65, 114, 116, 
    159, 160, 162, 297
  )

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "37.66"
    },
    "table": {
      "table_name": "cscart_product_variation_group_products",
      "access_type": "range",
      "possible_keys": [
        "idx_group_id"
      ],
      "key": "idx_group_id",
      "used_key_parts": [
        "group_id"
      ],
      "key_length": "3",
      "rows_examined_per_scan": 72,
      "rows_produced_per_join": 72,
      "filtered": "100.00",
      "index_condition": "(`softwarepirmam_hewadelivard_cscart_4`.`cscart_product_variation_group_products`.`group_id` in (45,340,273,66,219,284,161,272,158,307,268,350,115,320,65,114,116,159,160,162,297))",
      "cost_info": {
        "read_cost": "30.46",
        "eval_cost": "7.20",
        "prefix_cost": "37.66",
        "data_read_per_join": "1K"
      },
      "used_columns": [
        "product_id",
        "group_id"
      ]
    }
  }
}