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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0307d727c4150a64e56b3791da6d6ee2c0df107c7d5d0e7798bec4330e70ca12' 
  AND token = 'tjUjX6NuBfggHjOxCFCmg+m0oKSpaL6cJcgaDdyvVo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}