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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38eab8d4574923773ad504a5dafe156785b364410b3b31bf6f20d48dd0ad2a8f' 
  AND token = '25lfm3WfnotczMR4dCNvfy/aGQLGkLF6jNRwY1p026k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}