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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '409dfa5a3cce96e91d1e7be8246e7d91edef60be7e4508ff1d2ac8b33a02b1c4' 
  AND token = 'Xc3B2dJwD89JKChz4+svxi+1XPHv3qo4/EbdAhTb8dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}