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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '599644343f04eaf9f1181f2f9b5b04ddf7bf02cd407158b55b2c02e3459ea226' 
  AND token = 'Kf3OJqoRbId7c7zEbk8UDd6JfrvoZTc1mexRjtvWPBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}