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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d0bb6730bcda615eb8afa4fd00cb506f833ca81fb7cc9048647935b50d4a1cd' 
  AND token = '4gnB8qBkjim9RG8+IjiPGYLdjnILRipbL/pOC3/Vfdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}