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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a21408ef6e51784519db6de162ed2bae2f27101603065d4f6b504125c505e24' 
  AND token = 'K5BjIwW73x4lLNee8+rtDOADH+HySC329Hn/kyokLn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}