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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43555bc368596bab8c16b51ac681203f7a128931bc69c2031a2c3556e4f52f0' 
  AND token = 'hN/UYShtGc3m9V5QWhO8dsiH502zI/RrGog4L83GxWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}