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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b425d9fb62f1c9ee56fd3f2902ab37a1be724fca728a8f64aee9bad956b6d6b' 
  AND token = 'f0MWP0D4ZRjO8B7fyfcj8KIb+ZyhUVkyT0sMx4/v0KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}