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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621ed38341a64508659bfc5548668af30442bc130c84d91638d0bf2f7c4e6c7b' 
  AND token = 'fXTVQALM3ScMOr3cpxX7DniyAPvDEnzU/tC6zgn3fwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}