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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729ca45938191d74c3e09a3a8363b8a7ba856b2dbad783d5e09247a18845efc9' 
  AND token = 'R7vX46g07M/KnFsobt5cAQk53JisFU6OSfs1kRIovRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}