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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9de7bc188ee7df80246aea2c00217797027bc1235885c7d2c1d975d09fc4c301' 
  AND token = 's9D1oDxuhmi4E5FvKa70JmkhlZyElgJAodQHNN8cjZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}