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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '854c257a4d243f3c4ce2566b5a6cd481f166049b9adf6a6246cb940e13afed7b' 
  AND token = 'IseCP5ueE9tXef9reEHSYwLaI7xNv7Q5iDNBhcEK6cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}