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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12842755d1d94bd0b391b5e6b78a0551b070d91b902bb77fb57938943a77bc0f' 
  AND token = 'B7uufvZQt9kYj+vDLB9FhQrXP4ZgO8E4vmIxvunsgNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}