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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e1a9631dbd5386e8326f9dab711ab7e02253ffd9202bbe8a2883a24be77d44' 
  AND token = 'HZXkn5+lcjujEtlyyQ6Sf4+UxtkjeYUwFRflCiC/iLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00081

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}