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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64fb1addc0b000482768da9cb3f3a511fe8d25a32586f0eb69d5602a646d67a' 
  AND token = 'Pgx+mCu/wD65GEIJhI1GLsTmT/MHShxtoCHbRmolTcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}